Rate of Association of S35 and C14 in Plasma Protein Fractions after Administration of Na2S35O4, Glycine-C14, or Glucose-C14

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The incorporation of formate-C14, glycine-2-C14, adenine-4, 6-C14, and phosphate-P32 into nucleic acids.

nine labeled either with C'4 or N'5. Considerable controversy has developed as to which one of these tracer compounds gives an accurate measurement of the “relativeturnover-rate― of the nucleic acids. In order to determine the “absolute turnover rate― of the nucleic acids, it is necessary to know the specific activity of the immediate precursor of the nucleic acids. Since even the ident...

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Plasma Protein Labeled with Lysine-ε-c14

The metabolism of homologous plasma proteins, labeled with lysine-epsilon-C(14), after oral administration to dogs has been investigated. The speed of the various processes involved is indicated by the maximum rate of C(14) O(2) excretion which is attained within 1 to 4 hours, the prompt appearance of protein activity in the plasma and disappearance of non-protein activity from it, both virtual...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1959

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)69765-0